Micah® protects against reactive oxygen species (ROS) and other free radicals in UVA-I region (340-400 nm) and extends this protection into the visible spectrum (> 400 nm), a potential source for significant ROS generation, providing broader spectrum free radical prevention. And it does this remaining colorless in formula, oxidatively stable and photostable, without interfering with normal metabolism.
When applied in a vehicle with 0.20% Micah to ex vivo human skin explants at 2 mg/cm2 and the skin was then exposed to 10 J/cm2 UVA (320-400 nm) radiation, the following results were observed:
- Micah effectively prevented UVA-induced ROS, performing at parity with the non-irradiated vehicle
- Micah prevented secretion of IL-1α, a marker associated with skin inflammation, redness, irritation and skin barrier function
- Micah prevented secretion of IL-6, a marker associated with skin inflammation, redness, irritation and skin barrier function
- Micah significantly reduced the presence of 8-OHdG, a marker associated with photoaged skin
Features & Benefits:
- Skin Protectant (anti-radical properties)